Negamycin (hydrochloride)
Negamycin (hydrochloride) is a dipeptide antibiotic. Negamycin (hydrochloride) can restore dystrophin expression in skeletal and cardiac muscles in mdx Duchenne muscular dystrophy (DMD) murine model. Negamycin (hydrochloride) can bind to a partial sequence of the eukaryotic rRNA-decoding A-site. Negamycin (hydrochloride) can be studied in DMD research[1].
Product Specifications
UNSPSC
12352211
Target
Antibiotic
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
NC[C@@H](C[C@H](CC(NN(CC(O)=O)C)=O)N)O.Cl
Molecular Formula
C9H21ClN4O4
Molecular Weight
284.74
References & Citations
[1]Arakawa, M., et al., (2003) . Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice. Journal of biochemistry, 134 (5), 751–758.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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