Butropium (bromide)
Butropium bromide is a competitive mAChR antagonist. Butropium bromide blocks acetylcholine-mediated glandular secretion and muscle contraction signals, suppressing salivary gland secretion and respiratory smooth muscle spasms. Butropium bromide is promising for research of excessive salivation[1][2].
Product Specifications
CAS Number
29025-14-7
UNSPSC
12352005
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology
Smiles
[H][C@]12C[C@H](C[C@]([N+]2(C)CC3=CC=C(C=C3)OCCCC)([H])CC1)OC(C(CO)C4=CC=CC=C4)=O.[Br-]
Molecular Formula
C28H38BrNO4
Molecular Weight
532.51
References & Citations
[1]Sakamoto Y, et al. The Effect of Butropium Bromide as a Premedication for Depression of Salivation on Endoscopic Examination Using Double Blind Technique[J]. Nihon Kikan Shokudoka Gakkai Kaiho, 1977, 28 (1) : 20-24.|[2]Chiba S. Effect of N- (4-butoxybenzyl) hyoscyaminium bromide (butropium bromide) on the isolated, blood-perfused canine atrium preparation[J]. Japanese Heart Journal, 1980, 21 (5) : 753-759.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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