Ricinelaidic acid
Ricinelaidic acid, a 12-hydroxy fatty acid, is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 μM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50=10 and 7 μM, respectively) . Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats[1].
Product Specifications
CAS Number
540-12-5
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Calcium Channel; Endogenous Metabolite; Leukotriene Receptor
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC(CCCCCCC/C=C/C[C@H](O)CCCCCC)=O
Molecular Formula
C18H34O3
Molecular Weight
298.46
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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