Troriluzole (hydrochloride)
Troriluzole hydrochloride is a third-generation peptide precursor of Riluzole and is an orally active glutamate modulator. Troriluzole hydrochloride can reduce synaptic glutamate levels and enhance the uptake of synaptic glutamate. Troriluzole hydrochloride shows potential for treating Alzheimer's disease and Generalized Anxiety Disorder (GAD)[2].
Product Specifications
CAS Number
1926204-76-3
Product Name Alternative
BHV-4157 (hydrochloride)
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(CN(C)C(CNC(CN)=O)=O)NC1=NC2=CC=C(OC(F)(F)F)C=C2S1.Cl
Molecular Formula
C15H17ClF3N5O4S
Molecular Weight
455.84
References & Citations
[1]Schanzer B, et al. Novel investigational therapeutics for generalized anxiety disorder (GAD) . Expert Opin Investig Drugs. 2019 Nov;28 (11) :1003-1012.|[2]Huang LK, et al. Clinical trials of new drugs for Alzheimer disease. J Biomed Sci. 2020 Jan 6;27 (1) :18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
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