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Pyroglutamylleucine

Pyroglutamylleucine (pGlu-Leu) is an orally active peptide. Pyroglutamylleucine can be present in certain food protein hydrolysates and traditional Japanese fermented foods. Pyroglutamylleucine attenuates dysbiosis by increasing in the host antimicrobial peptide, Rattusin (HY-P11548) [1].

Product Specifications

CAS Number

[21282-11-1]

Product Name Alternative

PGlu-Leu; pyroGlu-Leu

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@@H]1CCC(N1)=O)=O

Molecular Formula

C11H18N2O4

Molecular Weight

242.27

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Shirako S, et al. Pyroglutamyl leucine, a peptide in fermented foods, attenuates dysbiosis by increasing host antimicrobial peptide. NPJ Sci Food. 2019 Oct 7;3:18.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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