Paroxetine (Standard)

Paroxetine (Standard) is the analytical standard of Paroxetine. This product is intended for research and analytical applications. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs) . Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches[1][2][3][4].

Product Specifications

CAS Number

[61869-08-7]

UNSPSC

12352100

Target

Adrenergic Receptor; Apoptosis; P2X Receptor; Reference Standards; Serotonin Transporter

Related Pathways

Apoptosis; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Cancer; Neurological Disease

Purity

99.79

Smiles

FC1=CC=C(C=C1)[C@H]2[C@@H](CNCC2)COC3=CC=C4OCOC4=C3

Molecular Formula

C19H20FNO3

Molecular Weight

329.37

References & Citations

[1]M Bourin, et al. Paroxetine: a review. CNS Drug Rev. Spring 2001;7 (1) :25-47|[2]Young-Woo Cho, et al. Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation. Cancers (Basel) . 2019 Jan 9;11 (1) :64.|[3]Malek Zarei, et al. Paroxetine attenuates the development and existing pain in a rat model of neurophatic pain. Iran Biomed J. 2014;18 (2) :94-100.|[4]S Lightowler, et al. Anxiolytic-like effect of paroxetine in a rat social interaction test. Pharmacol Biochem Behav. 1994 Oct;49 (2) :281-5.