NDM-1-IN-6

NDM-1-IN-6 (Compound 1) is a potent, selective and competitive New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor with a Ki of 0.72 μM. NDM-1-IN-6 has a synergistic antibacterial effect with the carbapenem antibiotic Meropenem (HY-13678) . NDM-1-IN-6 is mainly used for research on NDM-1-mediated multidrug-resistant bacterial infections[1].

Product Specifications

CAS Number

[80570-90-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Bacterial; Beta-lactamase

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OC1=CC=CC=C1C2=NN=C(N2CC=C)S

Molecular Formula

C11H11N3OS

Molecular Weight

233.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Spyrakis F, et al. Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1. ACS Med Chem Lett. 2017 Nov 26;9 (1) :45-50.