L-870812
L-870812 is a HIV-1 integration with integrase strand transfer inhibitor. L-870812 consistently blocks cell-free and cell-associated HIV-1 infection. L-870812 blocks subtype C and CRFO2_AG primary isolates. L-870812 can be used for the study of replication-deficient HIV-1 Ba-L (env) pseudovirus[1].
Product Specifications
CAS Number
410545-90-3
UNSPSC
12352005
Target
HIV Integrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(N(C1=C2C=CC=NC2=C(O)C(C(NCC3=CC=C(F)C=C3)=O)=N1)C)C(N(C)C)=O
Molecular Formula
C21H20FN5O4
Molecular Weight
425.41
References & Citations
[1]Terrazas-Aranda K, et al. Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection. Antimicrob Agents Chemother. 2008 Jul;52 (7) :2544-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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