JNJ-4929821
JNJ-4929821 (Compound 88), a triazole derivative, is a selective Methionine aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 15 nM over MetAP-1. JNJ-4929821 can be used for cancers like liver cancer, colorectal adenocarcinoma and pancreatic cancer research[1].
Product Specifications
CAS Number
836671-12-6
UNSPSC
12352005
Target
MetAP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=S(C1=CC=CS1)(N(CC2=CC=C(F)C=C2)CC3=NC=NN3)=O
Molecular Formula
C14H13FN4O2S2
Molecular Weight
352.41
References & Citations
[1]Yin SQ, et al. The development of MetAP-2 inhibitors in cancer treatment. Curr Med Chem. 2012;19 (7) :1021-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MetAP2
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