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YM-534

YM-534, an imidazole compound, is an anti-cancer agent. YM-534 inhibits HL-60 cells with an IC50 of 2.5 μM. YM-534 retards the processing of preribosomal to ribosomal RNA of HL-60 cells. YM-534 can be used for the study of promyelocytic leukemia[1].

Product Specifications

CAS Number

95923-66-3

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(OCC)C(C)(C)CCCCOC1=CC=C(OCCCCCN2C=CN=C2)C=C1

Molecular Formula

C24H36N2O4

Molecular Weight

416.55

References & Citations

[1]Kanamaru R, et al. Mechanism of action of the synthetic imidazole compound YM 534 on human promyelocytic leukemia line HL-60 cells. Anticancer Drug Des. 1989 Aug;4 (2) :137-44.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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