YM-534
YM-534, an imidazole compound, is an anti-cancer agent. YM-534 inhibits HL-60 cells with an IC50 of 2.5 μM. YM-534 retards the processing of preribosomal to ribosomal RNA of HL-60 cells. YM-534 can be used for the study of promyelocytic leukemia[1].
Product Specifications
CAS Number
[95923-66-3]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(OCC)C(C)(C)CCCCOC1=CC=C(OCCCCCN2C=CN=C2)C=C1
Molecular Formula
C24H36N2O4
Molecular Weight
416.55
References & Citations
[1]Kanamaru R, et al. Mechanism of action of the synthetic imidazole compound YM 534 on human promyelocytic leukemia line HL-60 cells. Anticancer Drug Des. 1989 Aug;4 (2) :137-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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