AM-0561
AM-0561 is a NIK inhibitor (Ki: 0.3 nM) . AM-0561 decreases p52 levels[1].
Product Specifications
CAS Number
[1202764-63-3]
UNSPSC
12352005
Target
NF-κB
Related Pathways
NF-κB
Field of Research
Cancer
Smiles
C[C@](C1=NC=CS1)(C#CC2=CN3C(C4=NC(N)=NC=C4Cl)=CN=C3C=C2)O
Molecular Formula
C18H13ClN6OS
Molecular Weight
396.85
References & Citations
[1]Demchenko YN, et al. Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB. Oncotarget. 2014 Jun 30;5 (12) :4554-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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