25C-NBOH (hydrochloride)
25C-NBOH hydrochloride is a derivative of 2C-C having an N- (2-hydroxybenzyl) addition at the amine and is a potent agonist of 5-HT receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively) [1].
Product Specifications
CAS Number
[1539266-20-0]
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
ClC1=CC(OC)=C(C=C1OC)CCNCC2=C(C=CC=C2)O.Cl
Molecular Formula
C17H21Cl2NO3
Molecular Weight
358.26
References & Citations
[1]Hansen M, et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem Neurosci. 2014 Mar 19;5 (3) :243-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT2 Receptor
Available Sizes
Curated Selection
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