CUDA (disodium)
CUDA disodium is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively[1]. CUDA disodium selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA disodium may be valuable for the research of cardiovascular disease[2].
Product Specifications
UNSPSC
12352211
Target
Epoxide Hydrolase; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cardiovascular Disease
Purity
98.0
Smiles
O=C(NC1CCCCC1)NCCCCCCCCCCCC(O)=O.[Na].[Na]
Molecular Formula
C19H36N2Na2O3
Molecular Weight
386.48
References & Citations
[1]Morisseau C, et al. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol. 2002 May 1;63 (9) :1599-608.|[2]Fang X, et al. Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. J Pharmacol Exp Ther. 2005 Jul;314 (1) :260-70.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
036099-AP 200 µL
GLT25D2, NT (GLT25D2, C1orf17, KIAA0584, Procollagen galactosyltransferase 2, Glycosyltransferase 25 family member 2, Hydroxylysine galactosyltransferase 2) (AP) discontinued
Sign In for Pricing
View Details 
orb2833873-01 20 µg
Recombinant Human CST1 Protein, N-His-SUMO & C-Strep
Sign In for Pricing
View Details orb2833873-02 50 µg
Recombinant Human CST1 Protein, N-His-SUMO & C-Strep
Sign In for Pricing
View Details orb2833873-03 100 µg
Recombinant Human CST1 Protein, N-His-SUMO & C-Strep
Sign In for Pricing
View Details 
134946-APC 100 µL
NXNL1 (TXNL6, Nucleoredoxin-like Protein 1, Thioredoxin-like Protein 6, RDCVF) (APC)
Sign In for Pricing
View Details