Phyltetralin

Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system[1][2].

Product Specifications

CAS Number

[123048-17-9]

UNSPSC

12352005

Target

ROS Kinase

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

COC[C@@H]1[C@@H](COC)[C@H](C2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)C1

Molecular Formula

C24H32O6

Molecular Weight

416.51

References & Citations

[1]Conrado GG, et al. Prospecting and Identifying Phyllanthus amarus Lignans with Antileishmanial and Antitrypanosomal Activity. Planta Med. 2020 Jul;86 (11) :782-789.|[2]Yuandani, et al. 1, 7, 8-trihydroxy 2-naphtaldehyde, ethyl 8-hydroxy-8-methyl-tridecanoate and 1-triacontanol from Phyllanthus amarus Schumach. & Thonn. inhibit phagocytic activity of human leucocytes[J]. Journal of Pharmacy and Pharmacology, 2019, 71 (9) : 1451-1457.