Brodimoprim-d6

Brodimoprim-d6 (Ro 10-5970-d6) is a deuterium labeled Brodimoprim. Brodimoprim, a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria[1].

Product Specifications

CAS Number

[1346599-93-6]

Product Name Alternative

Ro 10-5970-d6

UNSPSC

12352005

Target

Bacterial; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])OC(C=C1CC2=CN=C(N)N=C2N)=C(C(OC([2H])([2H])[2H])=C1)Br

Molecular Formula

C13H9D6BrN4O2

Molecular Weight

345.22

References & Citations

[1]Marchese A, et al. Brodimoprim: effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability. J Chemother. 1996;8 (3) :171-177. |[2]Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5 (6) :475-479.