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Alvimopan metabolite (hydrochloride)

Alvimopan metabolite hydrochloride is a peripherally restricted Opioid Receptor antagonist that inhibits the amplitude of electrically evoked contractions and spontaneous mechanical activity in guinea pig ileum[1].

Product Specifications

CAS Number

[170098-43-8]

UNSPSC

12352005

Hazard Statement

H302

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Purity

99.93

Smiles

C[C@]1(C2=CC(O)=CC=C2)[C@H](CN(CC1)C[C@@H](C(O)=O)CC3=CC=CC=C3)C.Cl

Molecular Formula

C23H30ClNO3

Molecular Weight

403.94

Precautions

H302

References & Citations

[1]Beattie DT, et al. The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. Naunyn Schmiedebergs Arch Pharmacol. 2007 May;375 (3) :205-20.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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