Zidebactam (Standard)

Zidebactam (Standard) is the analytical standard of Zidebactam. This product is intended for research and analytical applications. Zidebactam (WCK-5107) is a potent β-lactamase inhibitor[1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL[2].

Product Specifications

CAS Number

[1436861-97-0]

UNSPSC

12352100

Target

Bacterial; Beta-lactamase; Penicillin-binding protein (PBP) ; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C([C@@H]1CCCNC1)NNC([C@@H]2CC[C@@H]3C[N@]2C(N3OS(=O)(O)=O)=O)=O

Molecular Formula

C13H21N5O7S

Molecular Weight

391.40

References & Citations

[1]Sader HS, et al. WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases. J Antimicrob Chemother. 2017 Jun 1;72 (6) :1696-1703.|[2]Moya B, et al. WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones. Antimicrob Agents Chemother. 2017 May 24;61 (6) .