MCI-225 (hydrate hydrochloride)
MCI-225 (DDP-225) hydrate hydrochloride is a selective and orally active noradrenaline (NA) reuptake inhibitor with 5-HT3 receptor antagonism. MCI-225 hydrate hydrochloride has antidepressant-like and anxiolytic-like properties. MCI-225 hydrate hydrochloride can be used for the study of anxiety disorder[1][2].
Product Specifications
CAS Number
[476148-82-0]
Product Name Alternative
DDP-225 (hydrate hydrochloride)
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC1=CC2=C(N=C(N=C2S1)N3CCNCC3)C4=CC=CC=C4F.Cl.O
Molecular Formula
C17H20ClFN4OS
Molecular Weight
382.88
References & Citations
[1]Eguchi J, et al. The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism. Pharmacol Biochem Behav. 2001 Apr;68 (4) :677-83. |[2]Eguchi J, et al. Effects of a novel compound MCI-225 on impaired learning and memory in rats. Pharmacol Biochem Behav. 1994 Jun;48 (2) :345-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT3 Receptor
Curated Selection
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