KUNG29
KUNG29 is a potent and selective Grp94 inhibitor with a Kd of 0.2 μM. KUNG29 induces the degradation of integrin α2 in MDA-MB-231 cells[1].
Product Specifications
CAS Number
[1887032-92-9]
UNSPSC
12352005
Target
HSP
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(OC)C1=C(O)C=C(O)C(Cl)=C1CCC2=NC=CN2CC3=CC=CC=C3OCC
Molecular Formula
C22H23ClN2O5
Molecular Weight
430.88
References & Citations
[1]Arin N Graner, et al., HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line. Int J Hyperthermia. 2016 Dec 20;33 (3) :303–317.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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