LDN-193189 (dihydrochloride) (Standard)
LDN-193189 (dihydrochloride) (Standard) is the analytical standard of LDN-193189 (dihydrochloride) . This product is intended for research and analytical applications. LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].
Product Specifications
CAS Number
1435934-00-1
UNSPSC
12352100
Target
Organoid; Reference Standards; TGF-β Receptor
Related Pathways
Others; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Smiles
C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl
Molecular Formula
C25H24Cl2N6
Molecular Weight
479.40
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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