GSK-1292263 (hydrochloride)
GSK-1292263 (hydrochloride) is an orally active GPR119 agonist (pEC50 of approximately 6.9 and 6.7 nM for human and rat GPR119, respectively) . GSK-1292263 is used in the research of type 2 diabetes and dyslipidemia[1].
Product Specifications
CAS Number
[1032824-54-6]
UNSPSC
12352005
Target
GPR119
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
CC(C1=NOC(N2CCC(CC2)COC3=CN=C(C=C3)C4=CC=C(C=C4)S(C)(=O)=O)=N1)C.[H]Cl
Molecular Formula
C23H29ClN4O4S
Molecular Weight
493.02
References & Citations
[1]Zhu X, et al. GPR119 agonists: a novel strategy for type 2 diabetes treatment[J]. Diabetes mellitus–insights and perspectives, 2013: 59-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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