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BMS-442606

BMS-442606, the S-enantiomer of 6-hydroxybuspirone (6OHB), is an orally active 5-HT1A partial agonist. BMS-442606 can be used for generalized anxiety disorder (GAD) research[1].

Product Specifications

CAS Number

477930-31-7

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(N(CCCCN1CCN(C2=NC=CC=N2)CC1)C(C3)=O)[C@@H](O)C43CCCC4

Molecular Formula

C21H31N5O3

Molecular Weight

401.50

References & Citations

[1]Dockens RC, et al. Pharmacokinetics of 6-hydroxybuspirone and its enantiomers administered individually or following buspirone administration in humans. Biopharm Drug Dispos. 2007 Oct;28 (7) :393-402.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor

Frequently Asked Questions

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