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KRN-633 (Standard)

KRN-633 (Standard) is the analytical standard of KRN-633. This product is intended for research and analytical applications. KRN-633 is a potent VEGFR inhibitor with IC50s of 170, 160 and 125 nM for VEGFR1, VEGFR2 and VEGFR3, respectively.

Product Specifications

CAS Number

286370-15-8

UNSPSC

12352100

Target

Reference Standards; VEGFR

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

ClC1=CC(OC2=NC=NC3=CC(OC)=C(C=C32)OC)=CC=C1NC(NCCC)=O

Molecular Formula

C20H21ClN4O4

Molecular Weight

416.86

References & Citations

[1]Nakamura K, et al. KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. Mol Cancer Ther. 2004 Dec;3 (12) :1639-49.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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