KRN-633 (Standard)
KRN-633 (Standard) is the analytical standard of KRN-633. This product is intended for research and analytical applications. KRN-633 is a potent VEGFR inhibitor with IC50s of 170, 160 and 125 nM for VEGFR1, VEGFR2 and VEGFR3, respectively.
Product Specifications
CAS Number
[286370-15-8]
UNSPSC
12352100
Target
Reference Standards; VEGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=CC(OC2=NC=NC3=CC(OC)=C(C=C32)OC)=CC=C1NC(NCCC)=O
Molecular Formula
C20H21ClN4O4
Molecular Weight
416.86
References & Citations
[1]Nakamura K, et al. KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. Mol Cancer Ther. 2004 Dec;3 (12) :1639-49.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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