PF-04308515
PF-04308515 is a glucocorticoid receptor ligand. PF-04308515 inhibits IL-6, IFNγ production. PF-04308515 induces weak PGC1α interaction. PF-04308515 has antiinflammatory activities[1].
Product Specifications
CAS Number
1206876-95-0
Product Name Alternative
PF 4308515
UNSPSC
12352005
Target
Glucocorticoid Receptor; Interleukin Related; PGC-1α
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(C(C=C12)=CC=C2[C@]3(CC4=CC=CC=C4)C[C@@](C)(O)[C@@](C5=CC=CC=C5)(O)C[C@@]3([H])CC1=O)NC6=CC=CN=C6C
Molecular Formula
C35H34N2O4
Molecular Weight
546.66
References & Citations
[1]Hu X, et al. The antagonists but not partial agonists of glucocorticoid receptor ligands show substantial side effect dissociation. Endocrinology. 2011 Aug;152 (8) :3123-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6
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