AZD-8165
AZD-8165 is a highly selective neutral thrombin inhibitor. AZD-8165 is promising for research of cardiovascular diseases such as hypertension and heart failure[1].
Product Specifications
CAS Number
1201686-72-7
UNSPSC
12352005
Hazard Statement
H302-H373
Target
Thrombin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C([C@@H]1CC=NN1C([C@@H](C2=CC=C(F)C=C2)OC(CC)=O)=O)NCC3=CC(Cl)=CC=C3N4N=NN=C4
Molecular Formula
C23H21ClFN7O4
Molecular Weight
513.91
Precautions
P260-P264-P270-P330-P501
References & Citations
[1]Pokhodylo N, et al. The (1H-Tetrazol-1-yl) arenediazonium Salts as Convenient Reagents for Quinones Arylation: Synthesis of 1, 3-Benzoxathiol-2-ones and Naphtho [2, 1-d][1, 3] oxathiol-2-ones Bearing (1H-Tetrazol-1-yl) phenyl Motif[J]. Chemistry, 17 (2) : 304-314.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Frequently Asked Questions
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