AZD-8165

AZD-8165 is a highly selective neutral thrombin inhibitor. AZD-8165 is promising for research of cardiovascular diseases such as hypertension and heart failure[1].

Product Specifications

CAS Number

[1201686-72-7]

UNSPSC

12352005

Hazard Statement

H302-H373

Target

Thrombin

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C([C@@H]1CC=NN1C([C@@H](C2=CC=C(F)C=C2)OC(CC)=O)=O)NCC3=CC(Cl)=CC=C3N4N=NN=C4

Molecular Formula

C23H21ClFN7O4

Molecular Weight

513.91

Precautions

P260-P264-P270-P330-P501

References & Citations

[1]Pokhodylo N, et al. The (1H-Tetrazol-1-yl) arenediazonium Salts as Convenient Reagents for Quinones Arylation: Synthesis of 1, 3-Benzoxathiol-2-ones and Naphtho [2, 1-d][1, 3] oxathiol-2-ones Bearing (1H-Tetrazol-1-yl) phenyl Motif[J]. Chemistry, 17 (2) : 304-314.