Elesclomol-d2
Elesclomol-d2 (STA-4783-d2) is a deuterium labeled Elesclomol (HY-12040) . Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis) . Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research[1][2][3][4].
Product Specifications
Product Name Alternative
STA-4783-d2
UNSPSC
12352005
Target
Apoptosis; Cuproptosis; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Cancer
Smiles
S=C(C1=CC=CC=C1)N(NC(C([2H])([2H])C(NN(C(C2=CC=CC=C2)=S)C)=O)=O)C
Molecular Formula
C19H18D2N4O2S2
Molecular Weight
402.53
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12040S/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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