L-768673

L-768673 is a potent selective IKs blocker with antiarrhythmic effects. L-768673 plays important roles in both atrial and ventricular refractoriness as well as pacemaker function in the dog heart. L-768673 can be used for arrhythmias research[1].

Product Specifications

CAS Number

[177954-68-6]

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

O=C(CC1=CC=C(C=C1C(F)(F)F)C(F)(F)F)N[C@H]2C(N(C3=CC=CC=C3C(C4=CC=CC=C4)=N2)CC(F)(F)F)=O

Molecular Formula

C27H18F9N3O2

Molecular Weight

587.44

References & Citations

[1]Stump GL, et al. In vivo canine cardiac electrophysiologic profile of 1,4-benzodiazepine IKs blockers. J Cardiovasc Pharmacol. 2003 Jul;42 (1) :105-12.