L-768673
L-768673 is a potent selective IKs blocker with antiarrhythmic effects. L-768673 plays important roles in both atrial and ventricular refractoriness as well as pacemaker function in the dog heart. L-768673 can be used for arrhythmias research[1].
Product Specifications
CAS Number
[177954-68-6]
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(CC1=CC=C(C=C1C(F)(F)F)C(F)(F)F)N[C@H]2C(N(C3=CC=CC=C3C(C4=CC=CC=C4)=N2)CC(F)(F)F)=O
Molecular Formula
C27H18F9N3O2
Molecular Weight
587.44
References & Citations
[1]Stump GL, et al. In vivo canine cardiac electrophysiologic profile of 1,4-benzodiazepine IKs blockers. J Cardiovasc Pharmacol. 2003 Jul;42 (1) :105-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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