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LTURM 36

LTURM 36 (20i) is a PI3K inhibitor, with IC50 values ​​of 0.64 μM and 5.0 μM for PI3Kδ and PI3Kβ, respectively. LTURM 36 can be used in anticancer research[1].

Product Specifications

CAS Number

[1879887-94-1]

UNSPSC

12352005

Target

PI3K

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C1C2=C(OC(N3CCOCC3)=N1)C(C4=CC=CC5=C4C=CC=C5)=CC=C2

Molecular Formula

C22H18N2O3

Molecular Weight

358.39

References & Citations

[1]Morrison R, et al. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur J Med Chem. 2016 Mar 3;110:326-39.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kβ; PI3Kδ

Curated Selection

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