BE-16627B
BE-16627B is a metalloproteinase inhibitor. BE-16627B can be isolated from microbial cultures. BE-16627B can inhibit metalloproteinases in enzyme assays. BE-16627B reduces the number and size of HT1080 cell nodules on lung surface in mouse models. BE-16627B inhibits growth of HT1080 cells in mice. BE-16627B can be studied in anti-cancer research[1].
Product Specifications
CAS Number
[137530-61-1]
UNSPSC
12352211
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CC(C)[C@@H](C(O)=O)NC([C@H](CO)NC(C(CC(NO)=O)CC(C)C)=O)=O
Molecular Formula
C16H29N3O7
Molecular Weight
375.42
References & Citations
[1]Okuyama, A., et al., (1994) . Inhibition of growth of human tumor cells in nude mice by a metalloproteinase inhibitor. Annals of the New York Academy of Sciences, 732, 408-410.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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