SAS-1121
SAS-1121 is a subtype-selective sigma 2 receptor/PGRMC1 ligand with a Ki of 16.2 nM. SAS-1121 is 574-fold selective for the signma 2 receptor over the sigma 1 receptor. SAS-1121 is a tertiary amine. SAS-1121 can be studied in neurology-related research[1].
Product Specifications
CAS Number
2095551-67-8
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(N1CC[C@]2([H])C3=CC=C(N4CCN(CCC(OCC)=O)CC4)C=C3[C@@]1([H])C2)OCC5=CC=CC=C5
Molecular Formula
C28H35N3O4
Molecular Weight
477.60
References & Citations
[1]Sahn, J. J., et al., (2016) . Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype-Selective Ligands. ChemMedChem, 11 (6), 556-561.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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