CEP-6800
CEP-6800 is an inhibitor of PARP-1 with chemopotentiating ability. CEP-6800 attenuates irinotecan (HY-16562) - and Temozolomide (HY-17364) -induced poly (ADP-ribose) accumulation in LoVo as well as HT29 xenografts. CEP-6800 can suppress Calu-6 tumor growth. CEP-6800 can be studied in anti-cancer research[1].
Product Specifications
CAS Number
[609848-02-4]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(C2=C1C3=C(C4=C2CCC4)NC5=C3C=C(CN)C=C5)=O
Molecular Formula
C18H15N3O2
Molecular Weight
305.33
References & Citations
[1]Miknyoczki, S. J., et al., (2003) . Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly (ADP-ribose) polymerase inhibitor. Molecular cancer therapeutics, 2 (4), 371-382.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119992/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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