Anaxirone
Anaxirone is an anti-tumor agent. The epoxy group in its structure can interfere with the proliferation of tumor cells by alkylating biological macromolecules such as DNA. Anaxirone has dose-limiting toxicity (DLT) and gastrointestinal toxicity. Anaxirone can be used for research on solid tumors such as non-small cell lung cancer (NSCLC) [1].
Product Specifications
CAS Number
[77658-97-0]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(N(N(C1=O)CC2OC2)CC3OC3)N1CC4OC4
Molecular Formula
C11H15N3O5
Molecular Weight
269.25
References & Citations
[1]Fiebig HH, et al. Phase II trial of anaxirone in advanced non-small cell lung cancer. Cancer Treat Rep. 1987 May;71 (5) :539-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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