Piretanide-d4

Piretanide-d4 is the deuterium labeled Piretanide. Piretanide is an oral active, relatively safe and effective diuretic. Piretanide has the potential for the research of congestive heart failure with a potential advantage of having potassium-sparing properties. Piretanide can also be used for the research of hypertension[1][2].

Product Specifications

CAS Number

[1246816-90-9]

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Cardiovascular Disease

Solubility

10 mM in DMSO

Smiles

O(C1=C(C=C(C(O)=O)C=C1S(N)(=O)=O)N2C(CCC2([2H])[2H])([2H])[2H])C3=CC=CC=C3

Molecular Formula

C17H14D4N2O5S

Molecular Weight

366.42

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Carda-Broch S, et al. Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection. J Chromatogr Sci. 1999;37 (4) :93-102. |[3]Sherman LG, et al. Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure. Clin Pharmacol Ther. 1986;40 (5) :587-594.