YM 13650
YM 13650 is an orally active anti-nephritic agent. YM 13650 exhibits dose-dependent preventive and therapeutic effects in both the rat immune complex nephritis model and the mouse spontaneous lupus nephritis model. YM 13650 can inhibit the increase in urinary protein, improve serum cholesterol and urea nitrogen levels, alleviate renal pathological damage, and prolong the survival time of mice. YM 13650 can be used in the research of nephritic diseases[1].
Product Specifications
CAS Number
[87545-58-2]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(OC1=CC=CC(C2=CN3C(SC4=CC=CC=C34)=N2)=C1)CC(O)=O
Molecular Formula
C18H12N2O4S
Molecular Weight
352.36
References & Citations
[1]Yamada T, et al. [Effects of YM-13650 on experimental nephritis in rats and mice]. Nihon Yakurigaku Zasshi. 1991 Apr;97 (4) :199-207. Japanese.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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