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YM 13650

YM 13650 is an orally active anti-nephritic agent. YM 13650 exhibits dose-dependent preventive and therapeutic effects in both the rat immune complex nephritis model and the mouse spontaneous lupus nephritis model. YM 13650 can inhibit the increase in urinary protein, improve serum cholesterol and urea nitrogen levels, alleviate renal pathological damage, and prolong the survival time of mice. YM 13650 can be used in the research of nephritic diseases[1].

Product Specifications

CAS Number

87545-58-2

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=C(OC1=CC=CC(C2=CN3C(SC4=CC=CC=C34)=N2)=C1)CC(O)=O

Molecular Formula

C18H12N2O4S

Molecular Weight

352.36

References & Citations

[1]Yamada T, et al. [Effects of YM-13650 on experimental nephritis in rats and mice]. Nihon Yakurigaku Zasshi. 1991 Apr;97 (4) :199-207. Japanese.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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