Simvastatin acid-d6
Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin , is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
Product Specifications
CAS Number
2747915-75-7
Product Name Alternative
Tenivastatin-d6
UNSPSC
12352211
Target
HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C(O)C[C@H](O)C[C@H](O)CC[C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@H](OC(C(CC)(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)[C@]12[H]
Molecular Formula
C25H34D6O6
Molecular Weight
442.62
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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