Florantyrone
Florantyrone (Zanchol) is a bile-promoting agent. Florantyrone increases the volume of bile rather than the content of bile acids. Zanchol can stimulate the synthesis of cholesterol in the liver, significantly raising the plasma cholesterol level, increasing the weight of the liver, but has no significant effect on the synthesis of cholesterol in the intestine. Florantyrone can be used in research on biliary motility disorders[1][2][3].
Product Specifications
CAS Number
519-95-9
Product Name Alternative
Zanchol
UNSPSC
12352005
Target
Others
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Smiles
O=C(CCC(C1=CC2=C(C=C1)C3=CC=CC4=CC=CC2=C34)=O)O
Molecular Formula
C20H14O3
Molecular Weight
302.32
References & Citations
[1]MEEROFF M. Acción hidrocolerética de la florantirona [Hydrocholeretic action of florantyrone]. Prensa Med Argent. 1958 Mar 21;45 (12) :1272-6. Spanish.|[2]Raicht RF, et al. Effect of a hydrocholeretic agent (Zanchol) on sterol metabolism in rats. Gastroenterology. 1977 Mar;72 (3) :507-9.|[3]Turley SD, Dietschy JM. Effects of clofibrate, cholestyramine, zanchol, probucol, and AOMA feeding on hepatic and intestinal cholesterol metabolism and on biliary lipid secretion in the rat. J Cardiovasc Pharmacol. 1980;2 (3) :281-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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