Razoxane (Standard)

Razoxane (Standard) is the analytical standard of Razoxane. This product is intended for research and analytical applications. Razoxane (ICRF 159) is an antiangiogenic topoisomerase II inhibitor, can be used for the research of renal cell carcinoma (RCC) [1].

Product Specifications

CAS Number

[21416-67-1]

UNSPSC

12352100

Target

Reference Standards; Topoisomerase

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

CC(CN(CC(N1)=O)CC1=O)N(CC(N2)=O)CC2=O

Molecular Formula

C11H16N4O4

Molecular Weight

268.27

References & Citations

[1]J P Braybrooke, et al. A phase II study of Razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin Cancer Res.2000; 6 (12) :4697-704.|[2]F Wingen, et al. Antimetastatic effects of Razoxane in a rat osteosarcoma model. Clin Exp Metastasis.Jan-Mar 1987; 5 (1) :9-16.