Tifenazoxide (Standard)
Tifenazoxide (Standard) is the analytical standard of Tifenazoxide. This product is intended for research and analytical applications. Tifenazoxide (NN414) is a potent, orally active and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has antidiabetic effect, can inhibit glucose stimulated insulin release in vitro and in vivo, and has a beneficial effect on glucose homeostasis[1][2].
Product Specifications
CAS Number
279215-43-9
UNSPSC
12352100
Target
Potassium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Smiles
O=S1(N=C(NC2=C1SC(Cl)=C2)NC3(CC3)C)=O
Molecular Formula
C9H10ClN3O2S2
Molecular Weight
291.78
References & Citations
[1]Carr RD, et al. NN414, a SUR1/Kir6.2-selective potassium channel opener, reduces blood glucose and improves glucose tolerance in the VDF Zucker rat. Diabetes. 2003 Oct;52 (10) :2513-8.|[2]Hansen JB. Towards selective Kir6.2/SUR1 potassium channel openers, medicinal chemistry and therapeutic perspectives. Curr Med Chem. 2006;13 (4) :361-76.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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