TL-310

TL-310 is a novel, orally active Taxane analogue. TL-310 can be used in the research of solid tumors[1][2].

Product Specifications

CAS Number

[352697-38-2]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C([C@@H]([C@H](C1=CC=CO1)NC(OCC(C)C)=O)O)O[C@@H]2C(C)=C([C@H](C([C@]3(C)[C@H](C[C@@]([H])(OC4)[C@]4(OC(C)=O)[C@]3([C@@H]([C@@]5(C2)O)OC(C6=CC=CC=C6)=O)[H])O)=O)OC(C7CC7)=O)C5(C)C

Molecular Formula

C45H55NO16

Molecular Weight

865.92

References & Citations

[1]Glasspool R M, et al. A phase I study of a novel taxane, TL310, orally administered every week in patients (pts) with advanced solid tumors. Journal of Clinical Oncology, 2007, 25 (18_suppl) : 2544-2544. |[2]Harris N, et al. Abstract# 5438: Metabolism of the oral taxane TL310 in vitro and in a Phase I study[J]. Cancer Research, 2009, 69 (9_Supplement) : 5438-5438.