PPARα/γ/δ agonist 1
PPARα/γ/δ agonist 1 (Compound 2) is a potent PPARα/γ/δ agonist, with an IC50 of 70 nM for PPARγ. PPARα/γ/δ agonist 1 can be used for the research of type 2 diabetes[1].
Product Specifications
CAS Number
[853652-40-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
O=C(CN1C=CC2=C1C=CC(OCCCOC3=C(CCC)C4=CC=C(C(C5=CC=CC=C5)=O)C=C4C=C3)=C2)O
Molecular Formula
C33H31NO5
Molecular Weight
521.60
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Mahindroo N, et al. Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists. J Med Chem. 2006 Oct 19;49 (21) :6421-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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