PPARα/γ/δ agonist 1

PPARα/γ/δ agonist 1 (Compound 2) is a potent PPARα/γ/δ agonist, with an IC50 of 70 nM for PPARγ. PPARα/γ/δ agonist 1 can be used for the research of type 2 diabetes[1].

Product Specifications

CAS Number

[853652-40-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PPAR

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Smiles

O=C(CN1C=CC2=C1C=CC(OCCCOC3=C(CCC)C4=CC=C(C(C5=CC=CC=C5)=O)C=C4C=C3)=C2)O

Molecular Formula

C33H31NO5

Molecular Weight

521.60

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Mahindroo N, et al. Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists. J Med Chem. 2006 Oct 19;49 (21) :6421-4.