Lotifazole
Lotifazole (F 1686) is a non-steroidal anti-inflammatory agent. Lotifazole exhibits specific inhibition of delayed-type hypersensitivity and does not rely on the prostaglandin synthesis inhibition pathway at low doses. Lotifazole shows significant efficacy in treating paw edema induced by carrageenan in rats, erythema induced by ultraviolet radiation in guinea pigs, and pleurisy at high doses. Lotifazole can be used for the study of T-cell-mediated diseases[1].
Product Specifications
CAS Number
71119-10-3
Product Name Alternative
F 1686
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(NC1=NC(C2=CC=CC=C2)=CS1)OCC(Cl)(Cl)Cl
Molecular Formula
C12H9Cl3N2O2S
Molecular Weight
351.64
References & Citations
[1]Tarayre JP, et al. Lotifazole (F 1686), a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum. Agents Actions. 1984 Jan;14 (1) :93-101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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