Lotifazole
Lotifazole (F 1686) is a non-steroidal anti-inflammatory agent. Lotifazole exhibits specific inhibition of delayed-type hypersensitivity and does not rely on the prostaglandin synthesis inhibition pathway at low doses. Lotifazole shows significant efficacy in treating paw edema induced by carrageenan in rats, erythema induced by ultraviolet radiation in guinea pigs, and pleurisy at high doses. Lotifazole can be used for the study of T-cell-mediated diseases[1].
Product Specifications
CAS Number
71119-10-3
Product Name Alternative
F 1686
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(NC1=NC(C2=CC=CC=C2)=CS1)OCC(Cl)(Cl)Cl
Molecular Formula
C12H9Cl3N2O2S
Molecular Weight
351.64
References & Citations
[1]Tarayre JP, et al. Lotifazole (F 1686), a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum. Agents Actions. 1984 Jan;14 (1) :93-101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC881045-500 1x 500 µL
CD16 (C16/1045), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400225-100 1x 100 µL
Major Vault Protein (MVP) (1032), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 