DC-S238
DC-S238 is an orally active and highly selective histone methyltransferase SET7 (SETD7) inhibitor (IC50=4.88 μM) . DC-S238 is promising for research of cancer, diabetes and inflammatory diseases[1].
Product Specifications
CAS Number
[832109-48-5]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
O=C(OC)C1=C(SC(C(NC2=CC=CC([N+]([O-])=O)=C2)=O)=C1C)N
Molecular Formula
C14H13N3O5S
Molecular Weight
335.34
References & Citations
[1]Meng F, et al. Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening. J Med Chem. 2015 Oct 22;58 (20) :8166-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SETD7/KMT7
Curated Selection
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