BMS-317180
BMS-317180 is an orally active and potent growth hormone secretagogue receptor (GHS-R) agonist (EC50=7.9 nM) . BMS-317180 stimulates endogenous growth hormone (GH) release. BMS-317180 is promising for research of age-related frailty, osteoporosis, and cancer cachexia[1].
Product Specifications
CAS Number
[295337-71-2]
UNSPSC
12352005
Target
GHSR
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Smiles
O=C(NCCCCO)OCCN1N=NN=C1[C@@H](COCC2=CC=CC=C2)NC(C(N)(C)C)=O
Molecular Formula
C21H33N7O5
Molecular Weight
463.53
References & Citations
[1]Li J, et al. Discovery of a tetrazole-based growth hormone secretagogue: 4- (hydroxybutyl) carbamic acid 2-{5-[1- (2-amino-2-methylpropionylamino) -2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180) . J Med Chem. 2007 Nov 29;50 (24) :5890-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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