ACT-281959
ACT-281959 is an orally active prodrug of Selatogrel , a P2Y12 receptor antagonist. ACT-281959 can inhibit platelet aggregation and can be used for the research of cardiovascular disease[1].
Product Specifications
CAS Number
1159501-31-1
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(N1CCN(C([C@@H](NC(C2=NC(C3=CC=CC=C3)=NC(N4C[C@@H](OC)CC4)=C2)=O)CP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)=O)CC1)OCCCC
Molecular Formula
C38H55N6O14P
Molecular Weight
850.85
References & Citations
[1]Caroff E, et al. 4- ((R) -2-{[6- ((S) -3-Methoxypyrrolidin-1-yl) -2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl) piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. J Med Chem. 2015 Dec 10;58 (23) :9133-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y12 Receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940525-500 1x 500 µL
CD63 (MX-49.129.5), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040806-500 1x 500 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400679-100 1x 100 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680955-500 1x 500 µL
Mucin 1 / EMA / Episialin / CD227 (MUC1/955), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details