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JNJ-26993135

JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM[1].

Product Specifications

CAS Number

[841202-16-2]

UNSPSC

12352005

Target

Aminopeptidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Purity

99.30

Smiles

O=C(C1CCN(CC2=CC=C(OC3=NC4=CC=CC=C4S3)C=C2)CC1)O

Molecular Formula

C20H20N2O3S

Molecular Weight

368.45

References & Citations

[1]Marcos Lorca, et al. Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics. Journal of the Serbian Chemical Society 2023 Volume 88, Issue 1, Pages: 25-39.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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